کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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6284197 | 1296673 | 2012 | 5 صفحه PDF | دانلود رایگان |
By probing its functional anatomy, the default mode network (DMN) can be considered consisting of two interacting hub and non-hub subsystems. The hub subsystem includes posterior cingulate cortex (PCC), medial prefrontal cortex (MPFC) and bilateral inferior parietal cortex (IPC). The non-hub subsystem contains inferior temporal cortex (ITC) and (para) hippocampus (HC). In this study, Gaussian Bayesian Network (BN) and Gaussian Dynamic Bayesian Network (DBN) were applied separately to detect the instantaneous and temporal connection relationship within each and between the two DMN subsystems. It was found that the directional instantaneous interactions between the two subsystems were primarily “from non-hub to hub”. The temporal interactions between hub and non-hub regions, on the other hand, are less presented between the two subsystems. The hub subsystem demonstrated both strong instantaneous and temporal interactions among the hub regions, while the non-hub regions were only strongly inter-connected instantaneously but temporally isolated with each other. In addition, one of the hub regions, PCC, appears to be a confluent node and important in the functional integration within the network.
⺠The DMN interactions were presented as a “from non-hub to hub” pathway manner. ⺠The hub regions of DMN were both strong instantaneous and temporal connected. ⺠The non-hub regions were instantaneously inter-connected but temporally isolated. ⺠PCC appears to be a confluent node.
Journal: Neuroscience Letters - Volume 513, Issue 1, 28 March 2012, Pages 62-66