Effects of extracellular calcium concentration on neurite outgrowth in PC12 cells by staurosporine

► Staurosporine induces neurite outgrowth in PC12. ► Increasing extracellular Ca2+ increases staurosporine-induced neurite outgrowth in PC12. ► staurosporine uses the extracellular calcium ions to affect neurite outgrowth in PC12.