Involvement of GluR2 and GluR3 subunit C-termini in the trigeminal spinal subnucleus caudalis and C1-C2 neurons in trigeminal neuropathic pain

▶ ION-partial transection was performed in the GluR2 and GluR3 delta7 KI mice. ▶ Mechanical allodynia in the face was depressed. ▶ ERK phosphorylation in Vc neurons was depressed. ▶ Membrane trafficking of GluR2 and GluR3 subunits is involved in orofacial neuropathic pain.