کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6287121 1615570 2015 13 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Audibility, speech perception and processing of temporal cues in ribbon synaptic disorders due to OTOF mutations
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی سیستم های حسی
پیش نمایش صفحه اول مقاله
Audibility, speech perception and processing of temporal cues in ribbon synaptic disorders due to OTOF mutations
چکیده انگلیسی
These findings indicate that an impaired multivesicular glutamate release in OTOF-related disorders leads to abnormal auditory nerve fiber activation and a consequent impairment of spike generation. The magnitude of these effects seems to vary, ranging from no auditory nerve fiber activation to an abnormal generation of EPSPs that occasionally trigger a synchronized electrical activity, resulting in high-threshold CAPs.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Hearing Research - Volume 330, Part B, December 2015, Pages 200-212
نویسندگان
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