Distribution of glucocorticoid receptors and 11 beta-hydroxysteroid dehydrogenase isoforms in the rat inner ear

► We investigated the distribution of GRs and 11β-HSD isoforms in the rat inner ear. ► GRs and 11β-HSD1 were present in most cells in the rat inner ear tissues. ► Immunostaining of 11β-HSD2 was not observed in any of the inner ear tissues. ► Local steroid regulation by GRs and 11β-HSD is present in the inner ear.