In vivo virulence of commercial Saccharomyces cerevisiae strains with pathogenicity-associated phenotypical traits

►Saccharomyces cerevisiae is now considered to be an emerging opportunistic pathogen. ►Clinical and commercial strains were tested in murine models of systemic infection. ►Two commercial strains (“Cinta Roja” and Ultralevure) killed BALB/c mice. ►Both strains could develop fungemia via contaminated central venous lines. ►Both strains have capabilities to develop fungemia after a digestive translocation.