Effect of 1,25(OH)2D3 on BALB/c mice infected with Leishmania mexicana

- Mice infected and treated with vitamin D showed a reduction in lesion size.
- A decrease of epithelial atrophy and necrosis was shown in mice treated with vitamin D.
- Mice treated with vitamin D showed abundant and ordered collagen fibers.
- No differences in parasite burden were seen in mice with or without vitamin D treatment.
- A reduction in cytokines secretion was observed in mice treated with vitamin D.