Ability of TEP1 in intestinal flora to modulate natural resistance of Anopheles dirus

- Antibiotic-treated A. dirus became more susceptible to P. yoelii compared to control.
- In mosquitoes, the intestinal flora can regulate expression of TEP1.
- TEP1 gene plays an important role in the resistance of A. dirus to P. yoelii.
- The flora may modulate the development of P. yoelii in A. dirus by regulating TEP1 expression.