Entamoeba histolytica P-glycoprotein (EhPgp) inhibition, induce trophozoite acidification and enhance programmed cell death

- Overexpression of anti-Pgp5 transcript diminished P-glycoprotein expression.
- Inhibition of PGP produced acidification of intracellular pH.
- PGP overexpression prevent intracellular acidification and PCD.