Specific antibody to a conserved region of Babesia apical membrane antigen-1 inhibited the invasion of B. bovis into the erythrocyte

- RBCs invasion is a critical step in the pathogenesis and survival of Babesia spp.
- Central region of BbAMA-1 domain I and II as molecular vaccine target.
- Antibodies to rBbAMA-1P significantly inhibited the growth of Babesia bovis.
- Merozoites invasion into RBCs significantly inhibited by antibodies to rBbAMA-1P.