Molecular and biochemical characterisation of arginine kinases in Haemonchus contortus and Teladorsagia circumcincta

- T. circumcincta and H. contortus arginine kinase genes (1080 bp) encoded 360 amino acid proteins.
- TcAK and HcAK proteins had 99% similarity with each other and 94% similarity to C. elegans AK.
- Kinetic properties of recombinant TcAK and HcAK were very similar.
- Arginine analogues strongly inhibited enzyme activity.