Schistosoma mansoni egg glycoproteins and C-type lectins of host immune cells: Molecular partners that shape immune responses

► Schistosoma mansoni eggs can shape host immune responses. ► C-type lectin interactions with egg moieties play a major role. ► Individual egg glycoproteins carry complex glycans that bind different C-type lectins. ► Multivalency and molecular presentation of glycans may be important variables.