Recombinant thioredoxin peroxidase from Cryptosporidium parvum has more powerful antioxidant activity than that from Cryptosporidium muris

► Recombinant thioredoxin peroxidase of Cryptosporidium parvum and Cryptosporidium muris were expressed. ► Hydrogen peroxide consumption was greater in rCpTPx than in rCmTPx. ► Peroxidase activity of rCpTPx was highly enhanced by GSH, but that of rCmTPx was not. ► rCpTPx protected plasmid DNA from damage with only 12% of dose required with rCmTPx.