Pomegranate (Punica granatum) peel is effective in a murine model of experimental Cryptosporidium parvum

► Cryptosporidium parvum-infected mice showed weight loss, intestinal morbidity, and mortality. ► Mice treated with Punica granatum rapidly recovered from cryptosporidiosis. ► P. granatum treatments resulted in no adverse side effects. ► P. granatum is a promising efficient and safe treatment for cryptosporidiosis.