Susceptibility of a Brazilian wild rodent isolate of Schistosoma mansoni to praziquantel in mice

► The susceptibility of Schistosoma mansoni isolate from wild rodent to Praziquantel is unknown. ► The susceptibility was evaluated in mice. ► The wild isolate from Nectomys squamipes is susceptible to Praziquantel. ► Praziquantel was more effective against a laboratory isolate than the wild one.