Effectiveness of liposomal buparvaquone in an experimental hamster model of Leishmania (L.) infantum chagasi

► Leishmania infantum-infected hamsters were treated i.p. with liposomal buparvaquone at 0.33 mg/kg/day for eight consecutive days. ► This treatment reduced the parasite burden by 89% in the spleen and 67% in the liver. ► Buparvaquone showed a high in vitro selectivity index against Leishmania amastigotes.