Giardia duodenalis: Dendritic cell defects in IL-6 deficient mice contribute to susceptibility to intestinal infection

► IL-6 from bone-marrow derived non-T cells is required for immunity to Giardia. ► Transfer of dendritic cells with Giardia antigen induces protective immunity. ► Wild-type dendritic cells plus antigen can protect IL-6 deficient mice.