Photodynamic therapy for American cutaneous leishmaniasis: The efficacy of methylene blue in hamsters experimentally infected with Leishmania (Leishmania) amazonensis

► PDT promoted a decrease in the thickness of infected footpad in experimental ACL. ► PDT promoted reduction in the parasitic load in experimental ACL. ► MB + LED in ACL by Leishmania amazonensis shows a strong photodynamic effect. ► PDT using MB + LED is very promising in ACL caused by Leishmania amazonensis.