Schistosoma mansoni: N-acetylcysteine downregulates oxidative stress and enhances the antischistosomal activity of artemether in mice

► NAC enhances the therapeutic potential of artemether against adult Schistosoma mansoni. ► It downregulates S. mansoni-induced oxidative stress via GSH-dependent antioxidant enzymes. ► Administration of NAC + artemether improved serum markers of liver functions.