کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6314841 | 1619160 | 2016 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Organohalogenated contaminants in type 2 diabetic serum from Jeddah, Saudi Arabia
ترجمه فارسی عنوان
آلرژی آلژیناته شده در سرم دیابت نوع 2 از جده، عربستان سعودی
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم محیط زیست
شیمی زیست محیطی
چکیده انگلیسی
Most of the organohalogenated contaminants (OHCs) have high environmental stability and are lipophilic in nature, thus bioaccumulate through the various routes e.g., inhalation, dermal contact and food intake. Human exposure to these OHCs can induce adverse health effects. Studies on the occurrence of OHCs in human samples from Saudi Arabia are scarce. Therefore, this study aimed at providing preliminary insight on the occurrence of polychlorinated biphenyls (PCBs), organochlorine pesticides (OCPs) and polybrominated biphenyl ethers (PBDEs) in diabetic and non-diabetic donors from KSA. Serum samples were collected from type 2 diabetic patients (n = 40) and control donors (n = 20) to study the impact of OHCs on their health. For the first time we studied the difference of Æ©OHCs in type 2 diabetic and control participants. The order of obtained results was Æ©OCPs (35-650 ng/g lw)> Æ©PCBs (15-90 ng/g lw)> Æ©PBDEs (1.5-68 ng/g lw). The major contributors were p,pâ²-DDE (median 44 ng/g lw), PCB 153 (2.3 ng/g lw), PCB 138 (2.1 ng/g lw), BDE 153 (1.2 ng/g lw) and BDE 47 (0.85 ng/g lw). Exposure to different OHCs between male and female donors was not significantly different (p > 0.05). However, Æ©PCBs and Æ©OHCs were significantly higher (p < 0.05) in diabetic donors than those of control group. We computed significantly positive correlations (p < 0.05) among different OHCs and between OHCs and age factor. The current study highlights the presence of different OHCs in humans from Jeddah, KSA. This is a preliminary study based on small sample size but our results suggested that detailed studies are required to understand the sources of these pollutants and their impact on human health.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Environmental Pollution - Volume 213, June 2016, Pages 206-212
Journal: Environmental Pollution - Volume 213, June 2016, Pages 206-212
نویسندگان
Nadeem Ali, Nisreen Rajeh, Wei Wang, Khalid O. Abualnaja, Taha A. Kumosani, Hussain Mohammed Salem Albar, Syed Ali Musstjab Akber Shah Eqani, Iqbal M.I. Ismail,