کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6317887 | 1619176 | 2015 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Kinetic of NO2 uptake by Phleum pratense pollen: Chemical and allergenic implications
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم محیط زیست
شیمی زیست محیطی
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چکیده انگلیسی
Phleum pratense pollen was exposed to NO2 in a reactor allowing a continuous analysis of NO2 concentration by FTIR. The uptake coefficient of NO2 on pollen was calculated postulating a first order kinetic reaction and a value of (1.1 ± 0.1) Ã 10â7 was determined. NO2 uptake was faster when the pollen water content was increased and when the pollen was pre-treated with ozone. The effect of NO2 exposure on pollen allergic properties was investigated by quantifying Th2- and Th1-associated chemokines in a model of human dendritic cells. Cellular analysis clearly showed that cells exposed to fumigated pollen favored the production of chemokines known to promote Th2-cell responses. Altogether these data demonstrate that NO2 uptake by pollen directly correlates with increased Th2 response in human cells, and are in favor of the involvement of NO2 pollution in the increase of allergic diseases.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Environmental Pollution - Volume 196, January 2015, Pages 107-113
Journal: Environmental Pollution - Volume 196, January 2015, Pages 107-113
نویسندگان
Guillaume Chassard, Marie Choël, Sylvie Gosselin, Han Vorng, Denis Petitprez, Youcef Shahali, Anne Tsicopoulos, Nicolas Visez,