Are nails a valuable non-invasive alternative for estimating human exposure to phthalate esters?

Based on participant questionnaires and after performing multivariate statistics, the relevant parameters of exposure positively associated with PE metabolites in nails were the use of hand care products, weight of the individuals and sport activity hours. Based on the detected levels and aforementioned predictors, nails seem a valuable non-invasive matrix for estimating human long-term exposure to DEP, DBnP and/or DIBP and DEHP.