کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6351391 | 1622554 | 2016 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Urinary benzophenone concentrations and their association with demographic factors in a South Korean population
ترجمه فارسی عنوان
غلظت بنزوفن ادرار و ارتباط آن با عوامل جمعیت شناختی در جمعیت کره جنوبی
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کلمات کلیدی
بنزوفنون، ادرار بیومونیتوری انسانی، مشخصه هایه جمعیتی، جمعیت کره ای،
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم محیط زیست
بهداشت، سم شناسی و جهش زایی
چکیده انگلیسی
Benzophenone (BP) and its derivatives are widely used in various cosmetics, personal care products, and food packaging ink. The use of BP has raised concerns about the potential health risks associated with its endocrine-disrupting effects. This study evaluated urinary concentrations of BP derivatives in a national sample of the South Koreans population aged 6-89 years. From July to September in each 2010 and 2011, 1576 urine samples were collected. Urinary concentrations of benzophenone-1 (BP-1), benzophenone-2 (BP-2), benzophenone-3 (BP-3), benzophenone-4 (BP-4), benzophenone-8 (BP-8), and 4-hydroxybenzophenone (4-OH-BP) were analyzed using liquid chromatography-mass spectrometry. The detection rate for BP-1 and 4-OH-BP were 56% [limit of detection (LOD) 0.59Â ng/mL] and 88% (LOD 0.04Â ng/mL), respectively, whereas those for BP-2, BP-3, BP-4, and BP-8 were all below 25%. The geometric means of urinary BP-1 and 4-OH-BP concentrations were 1.24Â ng/mL and 0.45Â ng/mL, respectively. Multiple linear regression analysis indicated that concentrations of BP-1 in and of 4-OH-BP in adults were associated with sex and age. The BP-1 and 4-OH-BP concentration of children and adolescents was associated with sex, age, income, and current area of residence. The correlation was observed between urinary concentrations of BP derivatives, which is an important indication of exposure biomarkers and the metabolic pathways from BP-3. This is the first national study to evaluate the presence of BP derivatives in urine samples from the South Korean population, stratified by demographic factors.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Environmental Research - Volume 149, August 2016, Pages 1-7
Journal: Environmental Research - Volume 149, August 2016, Pages 1-7
نویسندگان
Hui-Seung Kang, Ahra Ko, Ji-Eun Kwon, Min-Sik Kyung, Gui Im Moon, Jae-Hong Park, Hee-Seok Lee, Jin-Hyang Suh, Jung-Mi Lee, Myung-Sil Hwang, Kisok Kim, Jin-Hwan Hong, In Gyun Hwang,