کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
636929 | 1456133 | 2009 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Chromatographic separation of proteins using hydrophobic membrane shielded with an environment-responsive hydrogel
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی شیمی
تصفیه و جداسازی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Chromatographic separation of proteins using hydrophobic membrane shielded with an environment-responsive hydrogel Chromatographic separation of proteins using hydrophobic membrane shielded with an environment-responsive hydrogel](/preview/png/636929.png)
چکیده انگلیسی
Environment-responsive membranes, suitable for carrying out hydrophobic interaction membrane chromatography (HIMC) were prepared by modification of a commercial hydrophobic microporous polyvinylidene fluoride (PVDF) membrane with a salt-responsive hydrogel composed of poly(N-vinyl lactam) cross-linked with bisacrylamide. These modified membranes were moderately hydrophobic in the presence of lyotropic salts but were quite hydrophilic in their absence. The membranes were characterized in terms of their mass gains after modification as well as their contact angles. These new membranes were found to be suitable for carrying out monoclonal antibody purification.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Membrane Science - Volume 345, Issues 1–2, 1 December 2009, Pages 177–182
Journal: Journal of Membrane Science - Volume 345, Issues 1–2, 1 December 2009, Pages 177–182
نویسندگان
R. Huang, K.Z. Mah, M. Malta, L.K. Kostanski, C.D.M. Filipe, R. Ghosh,