کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6369343 1623820 2016 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Stability of underdominant genetic polymorphisms in population networks
ترجمه فارسی عنوان
پایداری پلی مورفیسم های ژنتیکی زیرزمینی در شبکه های جمعیتی
کلمات کلیدی
زیرمجموعه، بازی هماهنگی، توپولوژی شبکه، سیستم دینامیک، ژنتیک جمعیت،
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک علوم کشاورزی و بیولوژیک (عمومی)
چکیده انگلیسی


- The role of underdominance in population connectivity is discussed.
- A simple model incorporating migration and underdominance in a meta-population with varying network topologies is presented.
- Simulations of underdominance with migration suggest the network topology of a meta-population is important to long term genetic stability.

Heterozygote disadvantage is potentially a potent driver of population genetic divergence. Also referred to as underdominance, this phenomena describes a situation where a genetic heterozygote has a lower overall fitness than either homozygote. Attention so far has mostly been given to underdominance within a single population and the maintenance of genetic differences between two populations exchanging migrants. Here we explore the dynamics of an underdominant system in a network of multiple discrete, yet interconnected, populations. Stability of genetic differences in response to increases in migration in various topological networks is assessed. The network topology can have a dominant and occasionally non-intuitive influence on the genetic stability of the system.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Theoretical Biology - Volume 390, 7 February 2016, Pages 156-163
نویسندگان
, ,