کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
637379 | 883685 | 2009 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Mineralization of biomimetically carboxymethylated collagen fibrils in a model dual membrane diffusion system
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موضوعات مرتبط
مهندسی و علوم پایه
مهندسی شیمی
تصفیه و جداسازی
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چکیده انگلیسی
In the present work, we show for the first time, that NÉ-carboxymethyllysine is the major product of the in vitro non-enzymatic glycation reaction between fibrillar collagen and glucuronic acid. Dual diffusion membrane system was effectively used for oriented crystal growth of octacalcium phosphate/hydroxyapatite on the biomimetically carboxymethylated collagen fibrils. We hypothesize that the function of biomimetically carboxymethylated collagen is to increase the local concentration of corresponding ions in such a way that a critical nucleus of ions can be formed, leading to the formation of the mineral under specific micro-environment conditions achieved by using diffusion membrane system.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Membrane Science - Volume 326, Issue 2, 20 January 2009, Pages 254-259
Journal: Journal of Membrane Science - Volume 326, Issue 2, 20 January 2009, Pages 254-259
نویسندگان
Hermann Ehrlich, Thomas Hanke, René Born, Christiane Fischer, Andrej Frolov, Tobias Langrock, Ralf Hoffmann, Uwe Schwarzenbolz, Thomas Henle, Paul Simon, Dorin Geiger, Vasily V. Bazhenov, Hartmut Worch,