Neoglycoconjugates of caseinomacropeptide and galactooligosaccharides modify adhesion of intestinal pathogens and inflammatory response(s) of intestinal (Caco-2) cells

► Hydrolyzed caseinomacropeptide (hCMP) was glycated with galactooligosaccharides (GOS). ► hCMP:GOS glycoconjugates significantly reduced pathogen adhesion to mucin. ► hCMP:GOS conjugates may affect interaction of virulence factors of L. monocytogenes. ► hCMP:GOS-Lu glycoconjugates inhibited the production of IL-1β by intestinal cells. ► This approach could be a new alternative to obtain multi-functional novel ingredients.