Impact of seed size on residual hypoglycin levels in ackee

► Different sized seeds from tree-ripened ackees were analyzed for hypoglycin B. ► Ackee arilli categorized by seed size were analyzed for hypoglycin A. ► Very small seeds had significantly less hypoglycin B than regular-to-medium seeds. ► Arilli associated with regular-to-medium sized seeds had lower hypoglycin A levels. ► Residual concentration of toxin in ackee is dependent on associated seed size.