کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
641079 1456984 2014 16 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Ozonation of acebutolol in aqueous solution: Ozonation by-products and degradation pathway
ترجمه فارسی عنوان
استحصال آسوبوتولول در محلول آبی: فرآورده های جانبی ازنژاد و مسیر تخریب
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی تصفیه و جداسازی
چکیده انگلیسی
In this study, ozonation was carried out at pH 2 (with the presence of radical scavenger), 7 and 12, in order to study the role of the ozone (O3) and hydroxyl radical (OH) in the transformation of acebutolol. Structure elucidation of the ozonation by-products was carried out using HPLC coupled with quadrupole time-of-flight high resolution mass spectrometry. Sixteen ozonation by-products were identified, of which fifteen have never been reported elsewhere. Based on the detected ozonation by-products, acebutolol can be degraded by both O3 and OH. When the O3 itself becomes a reactive species, the transformation of the acebutolol proceeded via the reaction between the O3 and the aromatic ring of the acebutolol to form the aromatic ring hydroxylated and aromatic ring opening by-products. Without the radical scavenger, ozonation at pH 7 and 12 showed that the transformation of the acebutolol proceeded via the involvement of the OH and different aliphatic chain degraded and hydroxylated by-products were detected.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Separation and Purification Technology - Volume 135, 15 October 2014, Pages 48-63
نویسندگان
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