کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6488766 1416481 2018 27 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Goat and cow milk powder-based diets with or without prebiotics influence gut microbial populations and fermentation products in newly weaned rats
ترجمه فارسی عنوان
رژیم های غذایی مبتنی بر پودر شیر و گاو با پری بیوتیک یا بدون آن، بر روی جمعیت های میکروبی روده و محصولات تخمیر در موش های تازه مرده
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی بیو مهندسی (مهندسی زیستی)
چکیده انگلیسی
The influence of goat and cow milk powders individually and in combination with prebiotics (inulin and oligofructose) on gut microbial populations, organic acid concentrations and gut morphology were studied in newly weaned rats fed for 21 days. The abundance of bacterial populations such as the Bacteroides-Prevotella-Porphyromonas group, Bifidobacterium spp. and Lactobacillus spp. in the gastrointestinal tract (ileum, caecum or colon) of rats were influenced by goat and cow milk powder-based diets. Clostridium perfringens was decreased significantly (P < 0.05) along the intestine in rats fed goat or cow milk diets. The inclusion of prebiotics into the diets significantly increased (P < 0.05) the abundance of bifidobacteria in the large intestine (caecum and colon). The majority of the increases in short-chain fatty acid (SCFA; acetic, butyric and propionic acids) concentrations in the caecum and colon were observed when prebiotics were added to the diet. In both the caecum and colon, fermentation indices of SCFA were significantly lower (P < 0.05) when the rats were fed goat milk diets, indicating that goat milk may have anti-inflammatory properties. There were no significant changes in the gut morphology (ileum villus length, colon crypt depth and goblet cells per crypt) of rats that consumed goat and cow milk diets. Overall, goat and cow milk powders individually and in combination with prebiotics had differential effects on gut microbiota composition and metabolism without affecting the intestinal epithelial cell architecture. These results offer a basis for dietary strategies that could be used to influence gut microbiota to achieve positive health benefits.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Food Bioscience - Volume 24, August 2018, Pages 73-79
نویسندگان
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