Environmentally friendly, microwave-assisted synthesis of 5-substituted 1 H-tetrazoles by recyclable CuO nanoparticles via (3+2) cycloaddition of nitriles and NaN3

We demonstrate that practical, simple, efficient and recyclable CuO nanoparticles can catalyze the (3+2) cycloaddition of nitriles and NaN3 to synthesize 5-substituted-1H-tetrazoles using microwave irradiation.