کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6552598 160445 2014 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Postmortem bone marrow analysis in forensic science: Study of 73 cases and review of the literature
ترجمه فارسی عنوان
تجزیه مغز استخوان پس از قاعدگی در علوم قانونی: مطالعه 73 مورد و بررسی ادبیات
کلمات کلیدی
مغز استخوان، تحقیقات پس از مدتی، کالبد شکافی قانونی، میلولد پلاسمی، مورفولوژی سلول، سپسیس،
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
چکیده انگلیسی
In forensic sciences, bone marrow (BM) is an alternative matrix in postmortem toxicology because of its good resistance to autolysis and contaminations. Nevertheless, few studies have been focused on postmortem BM morphological changes after pathological stimuli. We examined 73 BM samples from forensic autopsies; causes of death were both natural and traumatic. BM samples were collected from the sternum by needle aspiration and biopsy; in selected cases, immunohistochemistry was performed. Few autolytic changes were found; BM cellularity decreased with increasing age and postmortem interval. Notable cell changes were detected in 45 cases (61.64%): neoplastic (n = 4), and non-neoplastic BM findings (n = 41), including multiorgan failure/sepsis (n = 26), myelodisplastic-like conditions (n = 11), and anaphylactic reactions (n = 4). The results showed that BM cellularity supported circumstantial and autopsy findings, suggesting that BM samples could be a useful tool in forensic science applications.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Forensic Science International - Volume 234, January 2014, Pages 72-78
نویسندگان
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