کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6588728 | 1423241 | 2018 | 11 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Scale and causes of catalyst activity loss in enzymatic catalyzed reactive distillation
ترجمه فارسی عنوان
مقیاس و علل از دست دادن فعالیت کاتالیست در تقطیر واکنش کاتالیزوری آنزیمی
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
تقطیر مجدد، ستون دو جداره واکنشی ثبات آنزیم، آنزیم ها،
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی شیمی
مهندسی شیمی (عمومی)
چکیده انگلیسی
Continuous enzymatic catalyzed reactive distillation (eRD) is a new process that can reduce product inhibition and the need for additional purification steps. However, the enzymatic catalyst is exposed to markedly different conditions than in conventional processes. The enzyme stability, a crucial cost factor, has not been investigated for the application in an eRD and the underlying mechanisms for catalyst deactivation are still unknown. This article presents for the first time a comprehensive study on the scale and causes of enzyme activity reduction in eRD processes. Pilot plant experiments with the transesterification of butyl acetate with hexanol catalyzed by Novozyme 435 confirm the existence of a process window with high reaction rates and low activity loss. The remaining activity after 320â¯h of operation is investigated in each reactive packing, leading to a new found cause of activity reduction that has so far not been considered for enzymatic catalyzed reactive distillation. The results allow for a better design and operation of eRD processes and the development of enzyme immobilisates that cater to the specific needs of integrated operation.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Chemical Engineering Science - Volume 178, 16 March 2018, Pages 324-334
Journal: Chemical Engineering Science - Volume 178, 16 March 2018, Pages 324-334
نویسندگان
Torben Egger, Lisa S. Egger, Georg Fieg,