Silk fibroin aerogels for drug delivery applications

- Silk fibroin aerogels are synthesized using sol-gel and supercritical CO2 technology.
- SF aerogels are loaded with ∼21 wt% of ibuprofen using supercritical CO2.
- Greater than 99.98 wt% of ibuprofen is in the amorphous form.
- The ibuprofen release from SF aerogels occurs over a period of 6 h.
- Release of ibuprofen from SF aerogels is governed by Fickian diffusion.