کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
673361 1459504 2014 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
DSC study and calculation of metronidazole and clarithromycin thermodynamic melting parameters for individual substances and for eutectic mixture
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی جریان سیال و فرایندهای انتقال
پیش نمایش صفحه اول مقاله
DSC study and calculation of metronidazole and clarithromycin thermodynamic melting parameters for individual substances and for eutectic mixture
چکیده انگلیسی


• The system clarithromycin–metronidazole is a system with a simple eutectic.
• The eutectic melting temperature for the system clarithromycin–metronidazole is 155.2 ± 0.5 °C and it is not changed by varying the composition of the system.
• The DSC curve for the composition of 89:11 mol or 64.9:35.1 wt% corresponds to the eutectic (or the invariant) composition for the system clarithromycin–metronidazole.

In this study melting thermodynamic characteristics of clarithromycin and metronidazole as individual substances were investigated by DSC method. It was found that the binary system of clarithromycin and metronidazole is a system with simple eutectic. Composition, melting temperature and the heat of fusion of the eutectic were determined by calculation and experimental methods.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Thermochimica Acta - Volume 580, 20 March 2014, Pages 1–6
نویسندگان
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