کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6817995 | 547102 | 2016 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Work, meaning, and gene regulation: Findings from a Japanese information technology firm
ترجمه فارسی عنوان
کار، معنا و تنظیم ژن: یافته های یک شرکت فناوری اطلاعات ژاپنی
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کلمات کلیدی
تنظیم ژن، تندرستی، معنای کار، و وابستگی متقابل با دیگران،
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
علوم غدد
چکیده انگلیسی
The meaning in life, typically reflected in a sense of purpose, growth, or social embeddedness (called eudaimonic well-being, EWB), has been linked to favorable health outcomes. In particular, this experience is inversely associated with the conserved transcriptional response to adversity (CTRA), which involves up-regulation of genes linked to inflammation and down-regulation of genes linked to viral resistance. So far, however, little is known about how this transcriptome profile might be situated in specific socio-cultural contexts. Here, we tested 106 male workers at a large Japanese IT firm and found that the CTRA is inversely associated not only with general EWB but also with a more contextualized sense of meaning derived from the perceived significance of one's work and a sense of interdependence with others in the workplace. These results expand previous links between personal well-being and CTRA gene expression to include the socio-cultural determinants of meaning in life.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Psychoneuroendocrinology - Volume 72, October 2016, Pages 175-181
Journal: Psychoneuroendocrinology - Volume 72, October 2016, Pages 175-181
نویسندگان
Shinobu Kitayama, Satoshi Akutsu, Yukiko Uchida, Steve W. Cole,