کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6818997 | 547487 | 2015 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Cortisol level measurements in fingernails as a retrospective index of hormone production
ترجمه فارسی عنوان
اندازه گیری سطح کورتیزول در ناخن ها به عنوان شاخص گذشته نگر تولید هورمون
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کلمات کلیدی
کورتیزول، ناخن، فشار، مو
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
علوم غدد
چکیده انگلیسی
The cortisol level in fingernails may reflect the hormone's cumulative production over a long period, but the notions have not been fully established. In this study, we investigated the association of cortisol in fingernails with cortisol accumulation over a long period (hair cortisol) and over a relatively short period (salivary cortisol). In study 1, hair and fingernail samples were collected from 58 middle-aged and elderly men. The cortisol level in hair samples was moderately associated with the level in fingernail samples (r = 0.29, p < 0.05 and rs = 0.36, p < 0.01). In study 2, 37 workers provided 4 saliva samples over the course of one day (at awakening, 30 min after awakening, before lunch, and after work) and another set a month later. Further, the workers were asked to provide fingernail samples during a six-month period. We found that the cortisol level in saliva over the whole day (area under the curve for cortisol) was moderately associated with the cortisol level measured in fingernail samples that were collected 4 months (r = 0.43, p < 0.05 and rs = 0.50, p < 0.01) and 5 months later (r = 0.45, p < 0.05 and rs = 0.53, p < 0.01). These results indicated that the cortisol level in fingernail samples might retrospectively represent hormone production during a given period. The cortisol level in fingernail samples may be useful in the investigation of the link between psychosocial stress and health.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Psychoneuroendocrinology - Volume 54, April 2015, Pages 24-30
Journal: Psychoneuroendocrinology - Volume 54, April 2015, Pages 24-30
نویسندگان
Shuhei Izawa, Keiichi Miki, Masao Tsuchiya, Takeshi Mitani, Toru Midorikawa, Tatsuya Fuchu, Taiki Komatsu, Fumiharu Togo,