کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6876324 | 689780 | 2013 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Sorting genomes by generalized translocations
ترجمه فارسی عنوان
مرتب سازی ژنوم ها با ترشحات عمومی
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
الگوریتم، بازسازی ژنوم، انتقال
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی کامپیوتر
نظریه محاسباتی و ریاضیات
چکیده انگلیسی
Translocation is a prevalent rearrangement event in the evolution of multi-chromosomal species which exchanges ends between two chromosomes. A translocation is reciprocal if none of the exchanged ends is empty; otherwise, non-reciprocal. The problem of sorting by translocations asks to find a shortest sequence of translocations transforming one genome into another. The problem of sorting by reciprocal translocations can be solved in polynomial-time. Several algorithms have been developed for reciprocal translocation sorting. They can only be applied to a pair of genomes having the same set of chromosome ends. Such a restriction can be removed if non-reciprocal translocations are also allowed. In this paper, we show how to extend the algorithm for sorting by reciprocal translocations to include non-reciprocal translocations, allowing us to compare genomes containing different chromosome ends. We call this problem sorting by generalized translocations. We present a polynomial algorithm for this problem. At a conceptual level, there is some similarity between our algorithm and the algorithm developed by Hannenhalli which is used to sort genomes by reversals and translocations.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Theoretical Computer Science - Volume 491, 17 June 2013, Pages 127-135
Journal: Theoretical Computer Science - Volume 491, 17 June 2013, Pages 127-135
نویسندگان
Xiao Yin, Daming Zhu,