Molecular modeling and docking study on dopamine D2-like and serotonin 5-HT2A receptors

D2, D3, D4 and 5-HT2A receptors were modeled and refined by molecular dynamics simulations. Docking studies show the correlations between computed and experimental pKi is matched well. The homology models can be used as 3D templates for antipsychotic drug design and virtual screening in the future.