Multiplex Binding of Amyloid-like Protein Nanofilm to Different Material Surfaces

The development of a reliable universal way to form strongly bonded coating with underlying substrate independent on material chemistry is ideal surface modification strategy and remains great challenge. Herein the systematical studies on the adhesive strength of the amyloid-like coating on metal, organic and inorganic material surfaces reveal a novel multiplex bonding model on polar and non-polar abiotic surfaces, and different binding mode for respective material chemical structure including metal-sulfur coordination bonding, hydrogen bonding, electrostatic and hydrophobic interaction is elucidated with affirmative bonding strength.105