Dendrimer-entrapped gold nanoparticles modified with RGD peptide and alpha-tocopheryl succinate enable targeted theranostics of cancer cells

- Multifunctional Au DENPs modified with α-TOS and RGD peptide can be synthesized.
- The Au DENPs display enhanced therapeutic efficacy due to enhanced ROS generation.
- The Au DENPs specifically inhibit αvβ3 integrin-overexpressing cancer cells.
- The Au DENPs can be used as a nanoprobe for targeted CT imaging of cancer cells.