Galactosylated pullulan-curcumin conjugate micelles for site specific anticancer activity to hepatocarcinoma cells

- Galactosylated and nongalactosylated pullulan-curcumin conjugates were developed.
- The conjugates were self-assembled to micelles in aqueous medium.
- Galactosylation enhances toxicity of the conjugate toward HepG2 cells.
- Cellular uptake of the conjugate materialized via ASGPR mediated endocytosis.