Effective dentin restorative material based on phosphate-terminated dendrimer as artificial protein

- Fourth generation phosphate-terminated polyamidoamine dendrimer is successfully synthesized by one-step modification.
- As the analog of dentin phosphophoryn, it achieves effective remineralization on the demineralized human dentin.
- The regenerated mineral layers are thicker than 10 μm both in vitro and in vivo.