Biodegradable polymeric nanoparticles for oral delivery of epirubicin: In vitro, ex vivo, and in vivo investigations

- PLGA NPs were developed for oral delivery of epirubicin which was not reported yet.
- Improved intestinal transport of epirubicin could be achieved with PLGA NPs.
- In vivo oral bioavailability was increased 3.9 fold as compared to drug solution.