Comparative efficacy of chloramphenicol loaded chondroitin sulfate and dextran sulfate nanoparticles to treat intracellular Salmonella infections

- Chloramphenicol loaded chondroitin and dextran sulfate nanoparticles were developed.
- The prepared nanoparticles are hemo- and cyto-compatible.
- Dextran sulfate nanoparticles showed higher intracellular delivery in macrophages.
- Chloramphenicol loaded dextran sulfate nanoparticles showed enhanced activity against Salmonella.