Formulation and development of bicontinuous nanostructured liquid crystalline particles of efavirenz

- Comparative study between monoolein-based and phytantriol (PHY) based-cubosomes.
- Enhanced bioavailability with sustained release of single dose of EFV for 12 hrs.
- Characterization of PHY-based cubosomes mainly by SAXS and TEM.
- Stability studies of cubosomes in simulated gastric fluid.
- PK study of EFV cubosomes with a suspension and an MCT solution after oral administration.