Green-step assembly of low density lipoprotein/sodium carboxymethyl cellulose nanogels for facile loading and pH-dependent release of doxorubicin

- A simple and green approach was developed to produce a novel LDL/CMC nanogel via self-assembly.
- DOX was effectively encapsulated into the nanogels with an exceptionally high encapsulation efficiency.
- The release of DOX from DOX-LDL/CMC nanogels was pH-dependent.
- DOX-loaded nanogels effectively deliver the drug to cancer cells via endocytosis.