Fabrication of nano-structured calcium silicate coatings with enhanced stability, bioactivity and osteogenic and angiogenic activity

- Nanostructured CaSiO3 coating was fabricated by combining the APS and HT.
- HT treatment apparently decreased the degradation rate of CaSiO3 coating.
- Nanostructured topography increased the apatite mineralization ability.
- Nanostructured topography enhanced osteogenic and angiogenic activity.