A dual strategy for sensing metals with a nano 'pincer' scavenger for in vitro diagnostics and detection of liver diseases from blood samples

- A dual, non-invasive approach to detect the elevated level of metals in patients with liver disease.
- Organic scavenger molecule showed copper ions detection sensitivity of 1.35 × 10−2 μg/L in serum.
- Polymeric micellar inclusions showed tissue distribution for feasibility of directing to liver.
- Particles follow a faster kinetics and most of the micelles cleared from the circulation within 24 h.
- Polymeric micelles promises for drug delivery, diagnosis and treatment in the clinic.