Supramolecular curcumin-barium prodrugs for formulating with ceramic particles

- Labile drug molecules like curcumin are getting degraded upon contact with materials with high surface activity like ceramic particles.
- Nanoparticulate strategy could be explored for addressing this issue.
- Curcumin supramolecular prodrugs can be developed by complexing curcumin with barium.
- The prodrug along with micellisation strategy provides stability and release profile.
- An example of bottom up nanotechnology based formulatory approach to design new drug delivery systems to reduce drug-material incompatibility.